So, there's two major forms of inflammatory bowel disease. One is Ulcerative colitis and one is Crohn's Colitis. And they're too very different diseases, although they're similarly treated. So Crohn's Colitis or Crohn's Disease, is basically, inflammation of the gastrointestinal tract, and that can go anywhere, from the esophagus down to the rectum. That's just inflammations and ulcerations, that can happen and can be genetically related, it can be idiopathic. It's hard to say where it comes from, but the management is taking medications to help reduce the inflammation.
Now, on the other hand, Ulcerative colitis is inflammation of, just the colon and the disease just remains within the colon. And again, we need to take medications to decrease the inflammation, to help manage Ulcerative colitis.