So how to get rid of acne and pimples once and for all? This is sort of impossible, I don't wanna lie; however I think by far the best medicine we have for getting rid of acne and pimples once and for all is Accutane. Now let me explain a little bit about Accutane because I think there is a lot of confusion about what it is. Accutane is basically very strong vitamin A and it's a medicine that if you stay on it for six months, 99 percent of people's acne is gone and 70 percent of people's are so-called cured meaning they never really get significant acne again. It really is a wonder drug but it's a drug that needs to get respected. I think the cornerstone of any acne therapy is a retinoid. Retinoids are medicines like Retin-a, Tazorac or Atralin. You can also use over-the-counter Retinol. The reason these are so important is that they prevent the clogging of the pores which is really the first step in the development of any acne lesion, whether it be a pimple or whitehead or cyst. I also think something that kills bacteria can be helpful wheather this is a topizal antibiotic or a benzyl peroxide or a sulphur so anything like that that can kill bacteria. I think chemical peels if you can afford them are terrific for preventing and treating acne and I think the best spot treatment which I mentioned a bit earlier is a sulphur treatment. I think it's less irritating than salicylic acid and works better. They are very easy to find now; Clearasail makes one over the counter; Mario Bedescu's has sulphur in it; Proactiv has sulphur in it. These are very helpful in spot treatments.